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Old 04-01-2008, 02:17 PM   #1
 
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Talking evolence - new 12 month filler coming to market!!!!

a new dermal injectable filler that is made with natural collagen derived from pig tendons (yucky!) BUT the collagen is cross linked with sugar so there's no synthetic substances with it. they say this mimics the 3-d structure of your body's own collagen so it's identical to it. this makes the results more natural looking than other fillers according to the manufacturer of evolence. the best part is the results last up to 12 months! it sounds like it can be used for all the normal things you use an injectable filler for except the border of the lips or around the eyes (don't know why that's just what they say) this sounds promising i'd like to know when it will hit the u.s. market. The manufacturer is
'ColBar LifeScience' and right now evolence is in fda trial. yay soon we will get it!

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Old 04-03-2008, 09:08 PM   #2
 
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I've been following Evolence and I do not think it will prove to be popular. Since the active ingredient is derived from an animal, there are risks of reaction to the collagen (approximately 3% from what I recall) which is relatively high. That's 1 in 30 patients. That in addition to individual testing on the patient before they use the product is not appealing. I think what we'll see is Juvederm Ultra Plus and Perlane, the two longer-lasting hyaluronic acid injectable fillers, maintaining their lions shares of the market. Even a plastic surgery forum such as this reiterates these as being favorites among the fillers. The only thing I see knocking them off the top is another hyaluronic acid based filler which lasts longer than 6 to 9 months.

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Old 03-06-2009, 12:39 PM   #3
 
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My doctor in hong kong was quite excited to try it but it hasn't lived up to her expectations. While it's easy to inject it tends to 'bead up' making placement harder. I think the Restylane has a better feel when you press on the skin. Hopefully they'll work on it some more.

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